{"id":915,"date":"2026-06-22T21:05:49","date_gmt":"2026-06-22T21:05:49","guid":{"rendered":"https:\/\/www.vogelbusch-biocommodities.com\/technology\/starch-sugar-process-plants\/high-fructose-syrup-technology\/"},"modified":"2026-07-02T12:39:52","modified_gmt":"2026-07-02T12:39:52","slug":"high-fructose-syrup-technology","status":"publish","type":"page","link":"https:\/\/www.vogelbusch-biocommodities.com\/en\/technology\/starch-sugar-process-plants\/high-fructose-syrup-technology\/","title":{"rendered":"HFS Plants"},"content":{"rendered":"

Vogelbusch HFS Technology<\/h2>\n

High fructose syrup (HFS, or HFCS for high fructose corn syrup) in specified concentrations has a caloric value and sweetness similar to sucrose (table sugar). As a natural sweetener it is popular as liquid alternative to sucrose in the soft drinks and confectionery industry.<\/p>\n

High glucose syrup, which is the feedstock for HFS production, is obtained from common starch plants such as corn, wheat, rice and cassava.<\/p>\n

Starting out from starch milk, we design and supply production lines covering all process steps from the starch conversion through to final enrichment of the syrup.<\/p>\n\n

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For key figures for HFS plant construction<\/p>\n

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Block diagram<\/p>\n

\n Vogelbusch process for fructose production from starch milk\n <\/h3>\n
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Some of the glucose contained in high glucose syrup is converted to fructose and sold as HFS-42 or it is enriched to specified concentrations, such as HFS-55 and higher.<\/p>\n

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Clear substrate<\/p>\n

\n RAW MATERIAL PREPARATION\n <\/h3>\n
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The feedstock, high glucose syrup, is a clear substrate obtained from starch with a DE of 96 or higher (see glucose<\/a>) which is already filtered, deashed and evaporated to desired concentration for conversion.<\/p>\n\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n \n

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Isomerization<\/p>\n

\n BIOREACTION\n <\/h3>\n
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A portion of the glucose contained in the syrup is converted into fructose by an enzymatic conversion step called isomerization<\/strong>. <\/p>\n

To extend the lifetime of the enzymes, the ion content of the syrup is adjusted by addition of specific salts. This substrate then passes through columns that are filled with the immobilized enzyme isomerase, creating a glucose-fructose syrup also known as isoglucose, with a concentration of approximately 42 % fructose in dry matter substance.<\/p>\n

Isomerization can be designed for contents up to 48 % fructose in dry matter substance, for instance for the production of high purity fructose products (HFS-98, crystalline fructose).<\/p>\n\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n \n

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Enrichment to higher degrees<\/p>\n

\n PRODUCT ISOLATION, PURIFICATION AND CONCENTRATION\n <\/h3>\n
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The isoglucose syrup undergoes a purification step including ion exchange <\/strong>and decolorization<\/strong> (for instance by activated carbon treatment). <\/p>\n

In a continuous chromatographic<\/strong> separation<\/strong> process, the isoglucose syrup is separated in a fructose-rich (90 % pure extract) and a glucose-rich (raffinate) fraction.<\/p>\n

While the raffinate is recycled to the isomerization process, the extract is blended with isoglucose syrup to reach the desired content of 55 % fructose. After polishing of the solution in a mixed bed ion exchanger<\/strong> the product is finally concentrated to 77 % DS by multi-effect evaporation<\/strong> and marketed as HFS-55.<\/p>\n

Alternatively isoglucose syrup can be concentrated by evaporation<\/a> to 71 % DS and marketed as HFS-42.<\/p>\n\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n \n

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Product applications<\/strong><\/p>\n

Both HFS-42 and HFS-55 are commonly used in food, beverage and confectionery applications as in manufacturing the liquid product is easier to handle compared to crystalline sugar.<\/p>\n

The extract from chromatographic separation can be marketed directly or processed further.<\/p>\n

Typical applications are<\/p>\n