Bioreactor Design

We design the ideal fermenter for your process.

Design of bioreactor systems

Thanks to its extensive experience with microbial production techniques, Vogelbusch is well acquainted with the differing requirements of designing bioreactors. Besides its specific aeration systems Vogelbusch has the expertise in selecting the appropriate components and proven know-how, to run fermentations stable over longer periods.

2 bioreactor design
Customized bioreactor systems

Vogelbusch can take an idea from concept to full implementation. We develop the framework of a process based on the client’s test results.

The appropriate fermentation system is selected to align best with the individual process requirements. 

Vogelbusch also provides technical solutions for associated processes such as media preparation, downstream processing and auxiliary systems.

From lab to production scale

Specialized in upscaling biotechnological processes for the client, Vogelbusch executes projects on the basis of own and customers’ lab or pilot plant results. Based on individual process requirement the appropriate fermentation system and downstream operations are selected.

For the construction of facilities, we 

  • Establish detailed specifications of processing equipment and auxilliary facilities, and can provide operating and utility requirements
  • Deliver key equipment or turnkey
  • Monitor assembly and implementation
  • Train personnel
Numerous options

A multitude of process and apparatus solutions are available for your specific applications, including

  • Aerobic and anaerobic,
  • Sterile and non-sterile,
  • Batch and continuous,

as well as single fermenter and fermenter cascade solutions.

Selection criteria

For best performance a fermentation system is selected to fit process parameters (oxygen and nutrient supply, temperature, pH value, etc.) and considers sensitivity to mechanical stress. 

Further subjects of consideration are particular process requirements such as dissolved oxygen concentration, sterility, permissible concentration gradients or production scale. And we keep an eye on the overall economy of the plant, including investment and operating costs.

Some references for bioreactors


F.O. Licht's World Ethanol & Biofuels Conference

November 05 - 07, 2024 in Brussels, Belgium


A bioreactor system planned by VOGELBUSCH Biocommodities based on the Econutri concept ensures greater sustainability